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Trough level is the concentration of a drug in the body just before the next dose. It is used in therapeutic drug monitoring and clinical trials to measure drug effectiveness and safety.
23 wrz 2021 · Learn what peaks and troughs are, how they are measured, and why they are important for therapeutic drug monitoring. Find out how to calculate dosing intervals based on peak and trough levels for different medications.
A trough level is drawn when the drug is at its lowest in the bloodstream, right before the next scheduled dose is given. Medications have a predicted reference range of normal values for peak and trough levels.
Learn how to measure vancomycin trough levels to assess its efficacy and toxicity in MRSA infections. Find out the recommended target range, the optimal timing and the sources of clinical guidelines.
Trough level is the lowest concentration of a drug before the next dose. Learn how trough levels are measured and monitored for different drugs and conditions, such as liver transplantation, renal failure, and infections.
Learn how to individualize drug dosage by maintaining plasma or blood drug concentrations within a target range. Find out the characteristics, indications, examples and methods of therapeutic drug monitoring for various drugs, including aminoglycosides, vancomycin and flucloxacillin.
Learn about trough level, a measure of drug concentration in the blood, and its relevance for therapeutic drug monitoring. Find chapters and articles on trough level for various drugs, such as voriconazole, cyclosporine, and glycopeptides.
