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spike protein, SARS-CoV-2. The COVID-19 pandemic necessitated the rapid production of vaccines aimed at the production of neutralizing antibodies against the COVID-19 spike protein required for the corona virus binding to target cells.
- SARS-CoV-2 spike protein: pathogenesis, vaccines, and potential ...
Extensive glycan shielding of S protein that blocks the...
- SARS-CoV-2 spike protein: pathogenesis, vaccines, and potential ...
Extensive glycan shielding of S protein that blocks the protein surface may thereby, hide specific epitopes from antibody neutralization, thus, masking them and facilitate the immune evasion .
2 gru 2022 · As shedding of infectious virus is required for onward transmission, understanding shedding characteristics is relevant for public health interventions. Viral shedding is influenced by...
4 sty 2023 · We discovered that individuals who developed postvaccine myocarditis uniquely exhibit elevated levels of free spike protein in circulation, unbound by anti-spike antibodies, which appear to correlate with cardiac troponin T levels and innate immune activation with cytokine release.
8 mar 2024 · These data demonstrate that S protein stabilization with RBDs exposing highly conserved epitopes may be needed to increase the immunogenicity of spike proteins for future COVID-19 vaccines.
11 maj 2021 · Yet several online posts falsely claim that vaccinated people are “shedding” the SARS-CoV-2 spike protein, which is what the virus uses to enters cells, through their “ breath ” and “...
16 cze 2021 · The SARS-CoV-2 spike protein catalyzes the fusion of virions with host cells in a highly coordinated manner. The protein is synthesized as a single polypeptide chain that is...
