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  1. 29 sie 2013 · Risk factors for severe sepsis are related both to a patient's predisposition for infection and to the likelihood of acute organ dysfunction if infection develops.

  2. 1 lis 2014 · This review addresses the definitions, pathogenesis, clinical manifestations, management, and outcomes of patients with sepsis, severe sepsis, and septic shock.

  3. 23 maj 2016 · In its most severe form, sepsis causes multiple organ dysfunction that can produce a state of chronic critical illness characterized by severe immune dysfunction and catabolism. Much has been learnt about the pathogenesis of sepsis at the molecular, cell, and intact organ level.

  4. 4 paź 2021 · Sepsis has been a significant cause of mortality worldwide, and the recent viral pandemic that may produce severe sepsis and septic shock has been a major contributor to sepsis-related mortality. Understanding of the pathophysiology of sepsis has changed dramatically over the last several decades.

  5. 18 sty 2024 · Sepsis results when the response to infection becomes generalized and involves normal tissues remote from the site of injury or infection. The pathophysiology of sepsis and mechanisms of multiple organ system dysfunction are reviewed here.

  6. 21 lis 2013 · Clinical Features. The clinical manifestations of sepsis are highly variable, depending on the initial site of infec-tion, the causative organism, the pattern of acute organ dysfunction, the...

  7. 30 cze 2016 · Severe sepsis is defined as sepsis associated with organ dysfunction, hypotension or hyperfusion. Hypoperfusion abnormalities of end organs may include lactataemia, oliguria or an alteration in...

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