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12 cze 2023 · Sepsis syndromes span a clinical continuum with variable prognoses. Septic shock, the most severe complication of sepsis, carries a high mortality. Septic shock occurs in response to an inciting agent, which causes both pro-inflammatory and anti-inflammatory immune system activation.
6 wrz 2024 · For patients with septic shock associated with likely gram-negative sepsis, we suggest consideration of the use of two antibiotics from different classes to ensure effective treatment of resistant organisms.
1 sty 2020 · Septic shock—Circulatory, cellular, and metabolic abnormalities in septic patients, presenting as fluid-refractory hypotension requiring vasopressor therapy with associated tissue hypoperfusion (lactate > 2 mmol/L).
14 cze 2022 · Septic shock is a serious medical condition that can occur when an infection in your body causes extremely low blood pressure and organ failure due to sepsis. Septic shock is life-threatening and requires immediate medical treatment. It’s the most severe stage of sepsis.
29 sie 2013 · Clinical Features. The clinical manifestations of sepsis are highly variable, depending on the initial site of infection, the causative organism, the pattern of acute organ dysfunction, the...
30 lip 2024 · Septic Shock. July 30, 2024 by Josh Farkas. CONTENTS. Rapid Reference. Definitions of septic shock. Diagnosis & evaluation. Clinical Presentations. Biomarkers: NLR. Procalcitonin & CRP. Evaluation for the source. Sepsis mimics. Treatment. Vasopressors. Source control. Fluid. Steroid. DVT prophylaxis with heparin. Refractory shock. Methylene blue.
Timely administration of appropriate and effective antimicrobial therapy is a cornerstone of sepsis management. In 2006, a study of 2154 intensive care unit (ICU) subjects by Kumar et al [8] established the importance of antibiotic timing for the subpopulation of septic patients who have shock.
