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powiązane z: rna polymerase iii antibodyExpertise On Every Level To Craft Science & Technology Solutions In Life Science. Solving Problems In Life Science By Collaborating With the Global Scientific Community.
Recombinant Human/Mouse/Chimeric/Humanized Anti-RNA Polymerase II Antibody. Available for WB, Cyt, CyTOF, ELISA, FC, FuncS, ICC, IHC, Inhib, IP, Neut, RIA, cAMP Assay
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Anti-RNA polymerase III autoantibody in patients with SSc is associated with the diffuse cutaneous form of disease and an increased risk of sclerodermal renal crisis. A negative result indicates no detectable IgG antibodies to RNA polymerase III and does not rule out a diagnosis of SSc.
A positive result for RNA polymerase III antibody may support a diagnosis of systemic sclerosis (SSc) in the appropriate clinical context. Anti-RNA polymerase III autoantibody in patients with SSc is associated with the diffuse cutaneous form of disease and an increased risk of sclerodermal renal crisis.
We showed a significant positive association between a-RNA Pol III and occurrence of malignancy (p = 0.007), scleroderma renal crisis (p = 0.001) and decreased DLCO (p = 0.007). Anti-a-RNA Pol III antibodies are common in patients with SSc, particularly with a diffuse subtype.
Anti-RNA polymerase III antibodies (ARA) are a specific marker for Systemic Sclerosis (SSc), associated to severe disease with major organ and diffuse cutaneous involvement. In our series, ARA were found in 19 of 216 sera, in 15 cases as isolated antibodies' specificity, with a statistically negativ …
The presence of RNA polymerase III IgG antibody, when considered in conjunction with other laboratory and clinical findings, is an aid in the diagnosis of systemic sclerosis (SSc) with increased incidence of skin involvement and renal crisis with the diffuse cutaneous form of SSc.
1 maj 2017 · A variety of SSc-related ANA, including anticentromere antibody (ACA), antitopoisomerase I antibody (anti–topo I), and anti-RNA polymerase (RNAP) III antibody, have been well characterized and are used in our daily clinical practice.
In this review, we will focus on the clinical significance and interpretation of autoantibody data for clinicians, and provide a practical guide on the use of autoantibody tests for specific diseases.
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powiązane z: rna polymerase iii antibodyExpertise On Every Level To Craft Science & Technology Solutions In Life Science. Solving Problems In Life Science By Collaborating With the Global Scientific Community.
