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It has been shown that use of pyrimethamine is safe in rabbits when used at the right dosage. The anti-protozoal drug will directly attack the parasite, where it will both block the metabolism of folic acid in the parasite and increase the activity of trimethoprim-sulfa against the parasite.
Knowing that pyrimethamine has been safely used in rabbits to treat both toxoplasmosis and hepatic coccidial infections, Dr. van Praag suggested the possibility of using pyrimethamine to treat E. cuniculi in rabbits.
Sulfonamides are used in combination with pyrimethamine to treat protozoal diseases such as leishmaniasis and toxoplasmosis. (See also page Regulatory Considerations and Drug Withdrawal and Milk Discard Times.)
The effects of oral administration of sulfadoxine - pyrimethamine (SP), artesunate (A) and sulfadoxine - pyrimethamine - artesunate (SPA) on blood chemistry and brain serotonin in rabbits were investigated.
15 lis 2014 · In this study, Toxoplasma gondii antibodies in 77 free domestic rabbits from a rural area surrounding Shanghai, China were analyzed via ELISA, which identified 18 seropositive rabbits.
Toxoplasmosis. video. Toxoplasma gondii is an apicomplexan protozoan that infects humans and other warm-blooded animals worldwide, including birds and marine mammals. This intracellular parasite has a facultative, indirect life cycle, reproducing sexually in enterocytes from definitive hosts and asexually in nucleated cells from intermediate hosts.
20 gru 2011 · The findings in this study suggest that chloroquine treatment altered enzymatic antioxidant defense systems and elevated lipid peroxidation in the blood of rabbits with the most noticeable ...
