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Characteristics of neuropathic pain include spontaneous stimulus-independent pain and pain that is stimulus dependent and exhibits the features of allodynia and hyperalgesia. There are a variety of different mechanisms responsible for the generation of symptoms, which may be quite different from patient to patient. 18
24 lip 2023 · Pain is likely the most common symptomatic complaint in medicine; an understanding of its pathophysiology is critical to interpreting it in patients. Differentiating between the terms nociception and pain is worthwhile.
26 lut 2021 · The aim of this narrative review is to summarize the different pathogenic mechanisms underlying musculoskeletal pain and how these mechanisms interact to promote the transition from acute to chronic pain. Keywords: arthralgia, musculoskeletal pain, myalgia, neuroglia, physiology.
Nociceptive and inflammatory pains are physiological pain states, as they are protective and adaptive, whereas pathological pain is nonprotective and maladaptive. Nociception is the result of suprathreshold stimulation of peripheral nociceptors.
1 wrz 2018 · This chapter reviews the physiology and mechanisms of pain, as well as the pathways in the central and peripheral nervous system that transmit nociceptive information. The chapter divides the pain anatomical pathways into the peripheral nervous system, the spinal cord with the medullary dorsal horn system, and the ascending and supraspinal system.
Pain involves a complex interplay between messages sent from the periphery to the central nervous system and vice versa. Specific pathways play a vital role in carrying these messages, and modulating, or exacerbating their downstream effects.
5 cze 2012 · As shown by the definition, pain serves the purpose to prevent tissue damage and protect the body while it is healing. Under certain conditions, pain can become maladaptive and persist as chronic pain.
