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SC injection cold to reduce pain 2 mg/kg PO (dogs) and 1 mg/kg PO (cats) 8 mg/kg PO for motion sickness (dogs) Metoclopramide D2 dopaminergic antagonist 5-HT3 serotonergic antagonist 5-HT4 serotonergic agonist Antiemetic** Prokinetic agent Increases gastroesopha-geal sphincter tone 0.2–0.5 mg/kg PO, SC, or IM Q 8 H 1–2 mg/kg/day CRI
Ondansetron (brand names Zofran®, Zuplenz®) is an antiemetic used off label (extra label) to treat severe nausea and vomiting in dogs and cats. Many drugs are commonly prescribed for off-label use in veterinary medicine.
22 lip 2022 · The intravenous dose is 0.05 to 0.1 mg per pound (0.1 to 0.2 mg/kg). In cats, the usual dose is 0.11 mg per pound (0.22 mg/kg) every 8 to 12 hours. Ondansetron is a common medication that can be used to treat vomiting in dogs and cats. Read this article to learn more about dosage and side effects.
1 mar 2010 · Dolasetron is supplied as an injectable and as 50 mg tablets, which must be reformulated for use in cats. The empirical dosage is 0.6–1.0 mg/kg IV or PO sid. Oral dolasteron is approximately twice as expensive per mg as ondansetron, excluding reformulation costs.
Ondansetron is a 5-HT 3 receptor antagonist that is an effective anti-emetic in cats. The purpose of this study was to evaluate the pharmacokinetics of ondansetron in healthy cats.
5-HT 3 receptor antagonists (eg, ondansetron) are effective at alleviating chemotherapy-induced emesis in dogs and cats; however, they do not completely eliminate nausea. Metoclopramide has some 5-HT 3 receptor antagonist activity, but it is not as effective as the more selective drugs.
1 lis 2009 · Ondansetron (0.1-0.2 mg/kg q 6-12 h as a slow IV injection or for chemotherapy 0.5 mg/kg IV) is the prototypical drug in the class and is now a viable choice in veterinary medicine due to the low cost of generics.
