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Ondansetron (brand names Zofran®, Zuplenz®) is an antiemetic used off label (extra label) to treat severe nausea and vomiting in dogs and cats. Many drugs are commonly prescribed for off-label use in veterinary medicine.
22 lip 2022 · Ondansetron, commonly known by the brand name Zofran®, is used in dogs and cats to treat a variety of conditions with the most common being vomiting. It can also be used to treat sleep-apnea and pruritus (itching) in some pets.
CLASSIFICATION. USE. DOSE (for cats and dogs unless otherwise noted) Chlorpromazine. Alpha-2 adrenergic antagonist D2 dopaminergic antagonist H1 histaminergic antagonist M1 muscarinic cholinergic antagonist. Antiemetic. 0.2–0.4 mg/kg SC or IM Q 8 H. Cisapride. 5-HT4 serotonergic agonist.
Ondansetron is a 5-HT 3 receptor antagonist that is an effective anti-emetic in cats. The purpose of this study was to evaluate the pharmacokinetics of ondansetron in healthy cats.
Zofran is a medication that can treat nausea and vomiting in humans, but it is not approved for use in cats. Learn how Zofran works, what dosage to use, what side effects to watch out for, and what alternatives are available for cats.
Ondansetron is commonly used in veterinary medicine to prevent vomiting and nausea in cats. It is often used before or after surgery, to prevent the side effects of chemotherapy, or for the treatment of stomach or intestinal disorders. In addition to its common uses, ondansetron can also be used to treat motion sickness in cats.
5-HT 3 receptor antagonists (eg, ondansetron) are effective at alleviating chemotherapy-induced emesis in dogs and cats; however, they do not completely eliminate nausea. Metoclopramide has some 5-HT 3 receptor antagonist activity, but it is not as effective as the more selective drugs.
