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Nucleated RBCs are most often noted in dogs, cats and camelids in the context of strongly regenerative anemia. They can also be observed in camelids with regenerative anemias but even those that are not anemic but sick from various conditions.
Hemolysis may be caused by toxins, infections, abnormalities present at birth, drugs, or antibodies that attack the red blood cells. In dogs the most common cause of serious hemolysis is an antibody directed against that dog’s own red blood cells (immune-mediated hemolytic anemia).
28 mar 2018 · Clinical relevance: nRBC are most commonly seen in dogs, cats, and camelids with strongly regenerative anemias. Less commonly associated with other conditions such as lead poisoning, abnormal splenic function, bone marrow injury. nRBC are rare in cattle and horses, even with strongly regenerative anemias.
Learn about the veterinary topic of Red Blood Cells in Animals. Find specific details on this topic and related topics from the MSD Vet Manual.
Erythrocyte morphology should be evaluated using the 100x, oil immersion lens in an area of the smear where red cells are evenly spaced, usually slightly behind the feathered edge. Red blood cells are evaluated for changes in size, shape, color and inclusions. Erythrocytes are normally very uniform in size.
Red Blood Cells: The size, uniformity of size, and presence of microcytes, macrocytes, and abnormally shaped cells should be noted, along with cell color, uniformity of color, and the presence of hypochromasia, polychromasia, and nucleated RBCs.
1 lis 2009 · Nucleated red blood cells, also known as metarubricytes or normoblasts, can also be seen as part of a regenerative response as they are erythrocytes that are even less mature than polychromatophilic cells.
