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In this section, basic findings are reviewed from endocrinology, neurochemistry, and brain circuitry research conducted on patients with a diagnosis of PTSD (Table I). Table I. Summary of neurobiological features with identified abnormalities and functional implications in patients with post-traumatic stress disorder.
PTSD is associated with intrusive memories, distressing dreams, dissociative reactions, avoidance of trauma-related stimuli, negative cognition and mood, increased arousal and irritability, and clinically significant distress and impairment in functioning.
1 sty 2023 · Chemogenetic activation enhanced the firing and burst rates of VTA DA neurons in SPS-induced PTSD model rats and concomitantly mitigated the anxiety-like behavioral phenotypes.
Posttraumatic stress disorder (PTSD) has been impacting the functioning of a large number of people in military activities and victims of violence for many generations. However, investments in research aiming to understand the neurobiological ...
Traditional views of the neurochemistry of posttraumatic stress disorder (PTSD) focus on alterations in classical central nervous system neurotransmitters serotonin and norepinephrine and pathological reactivity in the hypothalamic-pituitary-adrenal (HPA) axis, and these are only briefly noted here.
THE NEUROCHEMISTRY OF PTSD. In PTSD there are a number of systems that get activated for the purpose of survival (Fig. 2 2). These include neurotransmitters such as dopamine, norepinephrine, epinephrine, opioid peptides, serotonin, GABA (gamma-aminobutyrate), glutamate, and acetylcholine, which are implicated in many psychological disorders.
11 wrz 2001 · PTSD affects multiple biological systems, such as brain circuitry and neurochemistry, and cellular, immune, endocrine and metabolic function. Treatment approaches involve a combination of...
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