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Microglia are a type of glial cell located throughout the brain and spinal cord of the central nervous system (CNS). [ 1 ] Microglia account for about 10–15% of cells found within the brain. [ 2 ] As the resident macrophage cells, they act as the first and main form of active immune defense in the CNS. [ 3 ]
21 mar 2024 · Microglia are a type of glial cell which are essential for the defense mechanisms in the central nervous system (CNS). Microglia share structural and functional similarities with tissue macrophages, highlighting their role in immune responses within the CNS.
30 wrz 2024 · Microglia, type of neuronal support cell (neuroglia) in the central nervous system of invertebrates and vertebrates that mediates immune responses by acting as macrophages, clearing cellular debris and dead neurons from nervous tissue through the process of phagocytosis (cell eating).
4 kwi 2017 · Microglia are resident cells of the brain that regulate brain development, maintenance of neuronal networks, and injury repair. Microglia serve as brain macrophages but are distinct from other tissue macrophages owing to their unique homeostatic phenotype and tight regulation by the central nervous system (CNS) microenvironment.
Microglial cells are the predominant parenchymal immune cell of the brain. Recent evidence suggests that like peripheral immune cells, microglia patrol the brain in health and disease.
22 paź 2019 · Microglial cells play a critical role when the brain suffers injury. However, these cells are constantly responding to neuronal signals by extending and withdrawing their processes from around synapses.
25 paź 2011 · Microglia — resident myeloid-lineage cells in the brain and the spinal cord parenchyma — function in the maintenance of normal tissue homeostasis. Microglia also act as sentinels of...
