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The condensation of interphase chromatin to form the compact chromosomes of mitotic cells is a key event in mitosis, critical in enabling the chromosomes to move along the mitotic spindle without becoming broken or tangled with one another.
The first five stages of M phase constitute mitosis, which was originally defined as the period in which the chromosomes are visibly condensed. Cytokinesis occurs in the sixth stage, which overlaps with the end of mitosis.
M phase is characterised by the enormous changes in the cytoskeleton, their assembly and breakdown, which serve to split the cytoplasm and replicate the genome into two parts. The M phase is divided into mitosis and cytokinesis, and the mitotic phase by itself has five subphases.
During mitosis, or M phase, the cell separates the duplicated copies of the genome and then separates the cytoplasm via cytokinesis. The mitotic cell cycle is how new somatic (nonreproductive) cells are generated in multicellular organisms.
After S phase, chromosome segregation and cell division occur in M phase (M for mitosis), which requires much less time (less than an hour in a mammalian cell). M phase involves a series of dramatic events that begin with nuclear division, or mitosis.
The eukaryotic cell cycle is divided into four phases: gap 1 (G1), synthesis (S), gap 2 (G2), and mitotic phase (M). A cell may reach a dormant state called gap 0 phase (G0) between M and G1, during which it is neither dividing nor prepared to divide.
G 2 is followed by mitosis (M), within which chromosome condensation, nuclear envelope breakdown, formation of mitotic spindles, attachment of chromosomes to the mitotic spindles, and separation of sister chromatids occur. The stages outside M phase are collectively known as interphase.
