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17 sie 2023 · Cephalexin is an antibiotic approved by the U.S. Food and Drug Administration (FDA) in 1970 and is classified as a first-generation cephalosporin. This drug is widely used in outpatient and inpatient healthcare settings due to its favorable safety and efficacy profile.
Keflex (cephalexin) and penicillin are antibiotics used to treat a variety of bacterial infections. Keflex and penicillin are in different drug classes. Keflex is a cephalosporin antibiotic, and penicillin is a penicillin-type antibiotic.
13 sie 2023 · FAQ. What is cephalexin? Cephalexin is a cephalosporin (SEF a low spor in) antibiotic. It works by fighting bacteria in your body. Cephalexin is used to treat infections caused by bacteria, including upper respiratory infections, ear infections, skin infections, urinary tract infections and bone infections.
Cefalexin is a useful alternative to penicillins in patients with penicillin intolerance. For example, penicillin is the treatment of choice for respiratory tract infections caused by Streptococcus, but cefalexin may be used as an alternative in penicillin-intolerant patients. [4] .
Cephalexin is also sometimes used for certain penicillin allergic patients who have a heart condition and are having a dental or upper respiratory tract (nose, mouth, throat, voice box) procedure, in order to prevent them from developing a heart valve infection.
A combination of three factors determines the antimicrobial activity of cephalosporins: penetration rate, β-lactamase susceptibility and penicillin-binding proteins (PBPs) inhibition. There is an interrelationship among these three factors and penetration rate may be important for Gram-negative bacteria.
12 paź 2023 · Cephalosporin allergies are diagnosed with skin testing and an oral challenge. Research shows you can react to cephalosporins and not penicillin. It is also common to have an allergy to only one cephalosporin and no others.