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Mediators of Inflammation is an open access journal that publishes papers on all types of inflammatory mediators, including cytokines, histamine, bradykinin, prostaglandins, leukotrienes, PAF, biological response modifiers and the family of cell adhesion-promoting molecules.
10 cze 2018 · Mediators of inflammation are regulatory molecules that control the generation, maintenance and resolution of this response, which is triggered after recognition of infection or injure. The initial recognition of the inflammatory stimuli leads to the production of pro-inflammatory mediators.
1 gru 2023 · Inflammatory mediators, such as bacterial product lipopolysaccharide (LPS) and cytokines such as interferon γ (IFN-γ), are potent inducers of iNOS gene expression. Activation of all isoforms is dependent on their binding to the cofactor calmodulin (CaM).
Pro-resolution lipid mediators promote resolution of inflammation in oral, lung, ocular, kidney, neural and gastrointestinal inflammatory diseases, as well as in ischaemia–reperfusion injury and...
21 gru 2015 · Specialized pro-resolving mediators (SPMs) are enzymatically derived from essential fatty acids and have important roles in orchestrating the resolution of tissue inflammation — that is ...
TRP channel-mediated effects in immune cells are diverse and range from regulation of cell migration and phagocytosis, to the production and release of inflammatory mediators. Furthermore, these channels mediate an active crosstalk between epithelial cells, neuronal tissue, and the immune cells that orchestrate immune responses to tissue damage ...
13 lut 2019 · There is now strong evidence to suggest that failed resolution may underpin autoimmune and inflammatory diseases and could thus be targeted to decrease inflammation. There are many molecules that have been described as mediators of resolution, and new players are still being continuously discovered.
