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Electrolytes carry electrical charge and are maintained to tight physiological concentrations through various mechanisms to ensure appropriate heart function (see ‘Standard serum concentrations’).
24 lip 2023 · Electrolytes are essential for basic life functioning, such as maintaining electrical neutrality in cells and generating and conducting action potentials in the nerves and muscles. Significant electrolytes include sodium, potassium, chloride, magnesium, calcium, phosphate, and bicarbonates.
28 lis 2005 · Electrolyte abnormalities are commonly associated with cardiovascular emergencies. These abnormalities may cause or contribute to cardiac arrest and may hinder resuscitative efforts. In some cases therapy for life-threatening electrolyte disorders should be initiated before laboratory results become available.
Effects of acid–base disorders on cardiovascular function are well known. Depression of the cardiac function is observed mainly with respiratory and metabolic acidosis, whereas respiratory alkalosis, mediated by a SNS, interferes on blood pressure and cardiac arrhythmias.
Electrolyte disorders can alter cardiac ionic currents kinetics and depending on the changes can promote proarrhythmic or antiarrhythmic effects. The present report reviews the mecha-nisms, electrophysiolgical (EP), electrocardiographic (ECG), and clinical consequences of elec-trolyte disorders.
1 cze 2022 · By modulating mitochondrial function, chloride channels play an important role in cardioprotection from ischemic-reperfusion injury and cardiac function. Additionally, Jiang et al.’s study demonstrated the upregulated CLIC1,4,5 is differentially expressed in patients with atrial fibrillation.
Electrolyte imbalances, particularly those involving potassium and sodium, pose critical considerations in the management of HF, as they may necessitate modifications in therapeutic strategies and have associations with patient prognosis .
