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  1. www.ncbi.nlm.nih.gov › books › NBK430847Depression

    17 lip 2023 · Pathophysiology. The underlying pathophysiology of major depressive disorder has not been clearly defined. Current evidence points to a complex interaction between neurotransmitter availability and receptor regulation and sensitivity underlying the affective symptoms.

  2. 2 kwi 2018 · Understanding depression pathophysiology is challenging because varying depression symptomatology cannot be explained by single hypothesis. Pathophysiologic mechanisms include: monoamine hypothesis, genetic, environmental, immunologic, endocrine factors and neurogenesis.

  3. 2 kwi 2018 · A number of factors (biogenic amine deficiency, genetic, environmental, immunologic, endocrine factors and neurogenesis) have been identified as mechanisms which provide unitary explanations for the pathophysiology of depression.

  4. The comprehension of the pathophysiology of the major depressive disorder (MDD) is essential to the strengthening of precision psychiatry. In order to determine the relationship between the pathophysiology of the MDD and its clinical progression, ...

  5. 9 lut 2024 · Introduction. Major depressive disorder (MDD), a main cause of disability worldwide, is characterized by physical changes such as tiredness, weight loss, and appetite loss.

  6. 18 lip 2023 · Depression is a common psychiatric disorder and a leading cause of disability worldwide. Here we conducted a genome-wide association study meta-analysis of six datasets, including >1.3 million...

  7. 10 kwi 2023 · Major depressive disorder is a clinical diagnosis; it is mainly diagnosed by the clinical history given by the patient and mental status examination. The clinical interview must include medical history, family history, social history, and substance use history along with the symptomatology.

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