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Cyclamate is an artificial sweetener (code E952) with a high sweetening power; according to numerous studies, in some people it can lead to the formation of a substance (CHA) which, when given in significant doses in animal testing, resulted in testicular damage.
Cyclamate is an artificial sweetener. It is 30–50 times sweeter than sucrose (table sugar), making it the least potent of the commercially used artificial sweeteners. It is often used with other artificial sweeteners, especially saccharin; the mixture of 10 parts cyclamate to 1 part saccharin is common and masks the off-tastes of both ...
In 1970, following the results of a controversial study in which rats given extremely high doses of cyclamate and other substances developed bladder tumors, cyclamate was banned in the United States from use in food, beverages and drugs.
Concerns about artificial sweeteners and cancer initially arose when early studies linked the combination of cyclamate plus saccharin (and, to a lesser extent, cyclamate alone) with the development of bladder cancer in laboratory animals, particularly male rats.
Sweeteners or sugar substitutes are food additives used to give a sweet taste to foods and beverages such as soft drinks, desserts, dairy products, sweets, chewing gum, and low-calorie and weight control products.
Cyclamate, odorless white crystalline powder that is used as a nonnutritive sweetener. The name usually denotes either calcium cyclamate or sodium cyclamate. Although they commonly are used as sweeteners in foods and beverages, cyclamates are banned in some places because of safety concerns.
12 lis 2020 · In this study, cyclamate content in 38 food samples including beverage, cake, candy, milk, and juice was analyzed using Ultra-Performance Liquid Chromatography, Tandem Mass Spectrometry...