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  1. CPT: 84480. Print Share Include LOINC® in print. Synonyms. T 3, Total. Special Instructions. This test may exhibit interference when sample is collected from a person who is consuming a supplement with a high dose of biotin (also termed as vitamin B7 or B8, vitamin H, or coenzyme R).

  2. T 3 Total - Total T 3 measurements are used to diagnose and monitor treatment of hyperthyroidism and are essential for recognizing T 3 toxicosis.

  3. CPT 84480 describes the measurement of total T3 in a patient’s blood. This article will cover the description, procedure, qualifying circumstances, appropriate usage, documentation requirements, billing guidelines, historical information, similar codes and billing examples.

  4. CPT codes are provided only as guidance to assist clients with billing. ARUP strongly recommends that clients confirm CPT codes with their Medicare administrative contractor, as requirements may differ.

  5. Measurement of free triiodothyronine is of value in confirming the diagnosis of hyperthyroidism, when an elevated free or total thyroxine level is found. Abnormal total and free triiodothyronine concentrations may appear in T 3 toxicosis, in the presence of normal thyroxine levels.

  6. While both T3 and T4 are bound to TBG, T3 is bound less firmly than T4. Total T3 consists of both the bound and unbound fractions. In hyperthyroidism, both T4 and T3 levels are usually elevated, but in a small subset of hyperthyroid patients, only T3 is elevated (T3 toxicosis).

  7. CPT CODE. 84480. INFORMATION. Triiodothyronine (T3) is the hormone principally responsible for the effects thyroid hormone on the various target organs. T3 (3, 5, 3’– triiodothyronine) is mainly formed extra-thyroidally, particularly in the liver, by enzymatic 5’–deiodination of T4.

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