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  1. 26 wrz 2018 · Cold shock proteins are multifunctional RNA/DNA binding proteins, characterized by the presence of one or more cold shock domains. In humans, the best characterized members of this family are denoted Y-box binding proteins, such as Y-box binding protein-1 (YB-1).

  2. The function of these cold shock proteins is to assist the cell in adapting to the sudden temperature change, allowing it to maintain as close to a normal level of function as possible. [7] One way cold shock proteins are thought to function is by acting as nucleic acid chaperones.

  3. 22 lip 2016 · Function of Cold Shock Proteins During Cold Shock. Csps have a highly conserved nucleic acid binding domain, called the cold shock domain (CSD) (Graumann and Marahiel, 1996). CSD contains two nucleic acid binding motifs, ribonucleoprotein 1 and 2 (Lee et al., 2013) that facilitate binding to target RNA and DNA (Chaikam and Karlson, 2010).

  4. Cold shock proteins are fascinating molecular entities that exhibit a unique structural composition, enabling them to perform their functions effectively. These proteins are typically small, with a highly conserved domain known as the cold shock domain (CSD).

  5. Cold shock proteins (Csps) comprise a family of small proteins that are structurally highly conserved and bind to single-stranded nucleic acids via their nucleic acid binding motifs RNP1 and RNP2.

  6. RNA-binding motif protein 3 (RBM3), an outstanding cold shock protein, is rapidly upregulated to ensure homeostasis and survival in a cold environment, which is an important physiological mechanism in response to cold stress.

  7. 9 lis 2021 · Cold shock protein (Csp) is a typical two-state folding model protein which has been widely studied by biochemistry and single molecule techniques. Recently two-state property of Csp was...

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