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  1. 26 cze 2024 · Clinical trials are a type of research that studies new tests and treatments and evaluates their effects on human health outcomes. People volunteer to take part in clinical trials to test medical interventions including drugs, cells and other biological products, surgical procedures, radiological procedures, devices, behavioural treatments and ...

  2. 25 wrz 2024 · This guidance updates and adapts the previous work of the World Health Organization (WHO) on research capacity for the context of well-designed and well-implemented clinical trials as framed in resolution WHA75.8 (2022). It aims to enhance clinical research efficiency, minimize research waste and provide guidance on sustained clinical trials that are always functional and active for endemic ...

  3. 4 cze 2022 · The safety profile of tirzepatide was consistent with previous findings in the SURPASS clinical trials in patients with type 2 diabetes, 23-27 and similar to other incretin-based therapies for the ...

  4. 20 lis 2024 · The BALANCE Investigators, for the Canadian Critical Care Trials Group, the Association of Medical Microbiology and Infectious Disease Canada Clinical Research Network, the Australian and New ...

  5. 20 lip 2022 · Pembrolizumab monotherapy has shown durable antitumor activity in advanced triple-negative breast cancer, 6-9 particularly as first-line therapy, with improved clinical responses observed among ...

  6. 10 lut 2021 · Weight loss of 10 to 15% (or more) is recommended in people with many complications of overweight and obesity (e.g., prediabetes, hypertension, and obstructive sleep apnea). 1,20,21,27 In the ...

  7. Clinical trials may also be referred to as interventional trials. Interventions include but are not restricted to drugs, cells and other biological products, surgical procedures, radiologic procedures, devices, behavioural treatments, process-of-care changes, preventive care, etc. This definition includes Phase I to Phase IV trials.

  8. Published: February 2023. The number of trials listed in the WHO International Clinical Trials Registry Platform (ICTRP) is reported by year, country, WHO region and income group for the period 1999–2022. Note that the ICTRP comprises both interventional and observational trials. See more on scope of ICTRP below. See also:

  9. 22 wrz 2021 · Malignant mesothelioma is an aggressive tumor arising from the serosal outer linings of the lungs (pleurae), heart, abdomen, and testes. Treatment trials have focused on malignant pleural ...

  10. 9 mar 2022 · Previously, the MONALEESA-7, MONALEESA-3, and MONARCH 2 trials have shown a significant overall survival benefit with the addition of a CDK4/6 inhibitor (either ribociclib or abemaciclib) in broad ...

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