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  1. Chronic pyelonephritis is continuing pyogenic infection of the kidney that occurs almost exclusively in patients with major anatomic abnormalities. Symptoms may be absent or may include fever, malaise, and flank pain. Diagnosis is with urinalysis, culture, and imaging tests. Treatment is with antibiotics and correction of any structural disorders.

  2. 22 maj 2024 · Chronic pyelonephritis is most commonly caused by chronic vesicoureteral reflux. Diagnosis is clinical and confirmed with imaging studies. Typically, a biopsy is not performed. There is no specific treatment, as damage is irreversible. May result in end-stage renal disease.

  3. For patients with severe pyelonephritis or with underlying debilitating conditions or obstruction, most guidelines recommend parenteral antibiotics, while those who are clinically stable are managed with oral antibiotics.

  4. 24 lis 2019 · Appropriate empiric antibiotics for inpatients with acute pyelonephritis include: An antipseudomonal carbapenem (imipenem or meropenem) plus vancomycin (for the most critically ill) Ceftriaxone (usually preferred for most cases)

  5. 19 cze 2020 · The penicillins (amoxicillin) and first-generation cephalosporins are the drugs of choice for chronic pyelonephritis because of good activity against gram-negative rods and good oral...

  6. 1 sie 2020 · Acute pyelonephritis is a bacterial infection of the kidney and renal pelvis and should be suspected in patients with flank pain and laboratory evidence of urinary tract infection. Urine...

  7. 21 lip 2023 · The increasing prevalence of antibiotic-resistant uropathogens highlights an urgent need for new therapeutic approaches that conserve antibiotic use and mitigate the morbidity associated with...

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