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Management of carcinoma in situ of the bladder remains a complex and challenging endeavor due to its high rate of recurrence and progression. Although it is typically grouped with other nonmuscle invasive bladder cancers, its higher grade and aggressiveness make it a unique clinical entity.
- Carcinoma In Situ of the Urinary Bladder: A Systematic Review of ...
New optical techniques have improved the detection of...
- Carcinoma In Situ of the Urinary Bladder: A Systematic Review of ...
Bladder carcinoma in situ (abbreviated “CIS”) is always high grade and requires immediate treatment. Bladder CIS presents itself as a flat, rash- or moss-like growth on the bladder lining. In some cases it may not be visible upon examination and only shows up when biopsy samples are examined by a pathologist.
15 lip 2020 · New optical techniques have improved the detection of carcinoma in situ (CIS) of the bladder. Bladder preservation using bacillus Calmette-Guérin immunotherapy remains the cornerstone of the treatment of CIS of the bladder.
15 lip 2020 · Carcinoma in situ (CIS) of the bladder is by definition a high-grade flat lesion confined to the mucosa, which is morphometrically similar to muscle-invasive bladder cancer (MIBC) [1]. CIS of the bladders displays a variable clinical behavior; the risk of muscle invasion in untreated patients is up to 80% and the disease-specific mortality may ...
30 lis 2021 · Concurrent carcinoma in situ (CIS) is an adverse prognostic factor; 4 hence, bladder biopsies from suspicious urothelium or mapping biopsies from normal-looking mucosa in patients with positive urine cytology, or a history of high-grade (HG) non-muscle-invasive bladder cancer (NMIBC) should be taken. 5 In patients with high-risk NMIBC ...
High-risk bladder cancer might include multiple or large high-grade stage 0a tumors, the presence of carcinoma in situ (stage 0is), and fast-growing stage I tumors. Treatment typically includes TUR with fulguration, followed by intravesical BCG therapy.
Treatment of bladder CIS differs from that of papillary transitional cell carcinoma (TCC). Endoscopic surgery, which is the initial treatment of papillary cancers, is not effective...
