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Often patients are being started on broad-spectrum empiric therapy that provides coverage of MRSA and Pseudomonas species. In general, the regimen includes a broad-spectrum β-lactam (eg, piperacillin/tazobactam, cefepime, meropenem) plus an agent with MRSA coverage such as vancomycin.
- Initial antimicrobial management of sepsis - PMC - PubMed Central (PMC)
The need for immediate broad-spectrum empiric antimicrobial...
- Antimicrobial Therapy and Antimicrobial Stewardship in Sepsis
The Surviving Sepsis Campaign guidelines recommend...
- Evidence review for managing and treating suspected sepsis in acute ...
Currently, it is recommended that broad spectrum antibiotics...
- Initial antimicrobial management of sepsis - PMC - PubMed Central (PMC)
26 sie 2021 · The need for immediate broad-spectrum empiric antimicrobial therapy for selected patients with severe sepsis may be life-saving, but may also put pressure to overuse antibiotics and drive antibiotic resistance.
The need for immediate broad-spectrum empiric antimicrobial therapy for selected patients with severe sepsis may be life-saving, but may also put pressure to overuse antibiotics and drive antibiotic resistance.
30 mar 2022 · Sepsis is a leading cause of death and disability, and healthcare organizations, professional societies, and regulatory agencies emphasize early broad-spectrum antibiotic therapy to improve patient outcomes.
The Surviving Sepsis Campaign guidelines recommend administering empirical, broad-spectrum antibiotics within an hour of triage for patients with sepsis and septic shock [14].
Currently, it is recommended that broad spectrum antibiotics be administered within one hour of presentation in higher risk categories. But beyond the apparent benefits, broad-spectrum antibiotics can cause considerable harm, including antibiotic-associated adverse effects and antibiotic resistance.
6 cze 2022 · Sepsis is a life threatening organ dysfunction caused by a dysregulated response to infection. 1 Early treatment with appropriate antimicrobials may improve outcome, but antimicrobial overuse can cause harm and contribute to antimicrobial resistance. 2 3 The multiple guidelines, statements, recommendations, and standards around the choice and ...
