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1 wrz 2001 · ATP synthase is a ubiquitous, highly conserved enzyme that catalyses the formation of ATP from ADP and P i using a unique rotary motor mechanism. The enzyme is located in the inner membrane...
- Nature
Chętnie wyświetlilibyśmy opis, ale witryna, którą oglądasz,...
- The six steps of the complete F 1 -ATPase rotary catalytic cycle - Nature
F1Fo ATP synthase interchanges phosphate transfer energy and...
- Structure of ATP synthase under strain during catalysis
CryoEM of mitochondrial ATP synthase frozen during rotary...
- Nature
ATP synthase is an enzyme that catalyzes the formation of the energy storage molecule adenosine triphosphate (ATP) using adenosine diphosphate (ADP) and inorganic phosphate (P i). ATP synthase is a molecular machine. The overall reaction catalyzed by ATP synthase is: ADP + P i + 2H +out ⇌ ATP + H 2 O + 2H +in.
5 wrz 2024 · We determined the structure of ATP synthase within mitochondria of the unicellular flagellate Polytomella by electron cryo-tomography and subtomogram averaging at up to 4.2-angstrom resolution, revealing six rotary positions of the central stalk, subclassified into 21 substates of the F 1 head.
3 sie 2021 · F1Fo ATP synthase interchanges phosphate transfer energy and proton motive force via a rotary catalysis mechanism. Isolated F1-ATPase catalytic cores can hydrolyze ATP, passing through six ...
Lai et al. determine the complete structures of human ATP synthase in three main rotational states and one substate, providing mechanistic insights into the structure and function of the ATP synthase complexes and laying a foundation for target-based drug discovery.
25 kwi 2022 · CryoEM of mitochondrial ATP synthase frozen during rotary catalysis reveals dramatic conformational changes in the peripheral stalk subcomplex, which enable the enzyme’s efficient synthesis of...
26 lis 1999 · Adenosine triphosphate (ATP) synthase contains a rotary motor involved in biological energy conversion. Its membrane-embedded F 0 sector has a rotation generator fueled by the proton-motive force, which provides the energy required for the synthesis of ATP by the F 1 domain.
