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14 paź 2024 · Animal models have been the cornerstone of biomedical research for decades. They provide invaluable insights into human disease mechanisms, preventative and therapeutic targets, and treatment...
This article reviews the use of non-human animals in biomedical research from a historical viewpoint, providing an insight into the most relevant social and moral issues on this topic across time, as well as to how the current paradigm for ethically ...
31 mar 2023 · Although its use is controversial and raises ethical challenges, the contribution of animal models in medicine is essential for understanding the physiopathology and novel treatment alternatives for several animal and human diseases.
Animal studies have been an essential component of every field of medical research and have been crucial for the acquisition of basic knowledge in biology. In this chapter a few of the contributions of such studies in biomedical and behavioral research will be chronicled.
There are several reasons why the use of animals is critical for biomedical research: • Animals are biologically very similar to humans. In fact, mice share more than 98% DNA with us! • Animals are susceptible to many of the same health problems as humans – cancer, diabetes, heart disease, etc.
Research in animal models have led to breakthrough insights in areas including: Cell biology. Genetics. Evolution. Embryonic development. Creation of induced pluripotent stem cells. Circadian rhythms and sleep regulation. Telomeres and telomerase (regulators of cell aging) Innate and adaptive immune systems. Brain and nervous system.
1 sty 2018 · There have been many medical advances due to research with animals. Whether animals are truly needed in medical research is debated on ethical grounds, but disease treatments and vaccines for humans and animals have been developed based on studies with animal models.