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21 lis 2023 · For urinary tract infections caused by E. coli, 1 in 5 cases exhibited reduced susceptibility to standard antibiotics like ampicillin, co-trimoxazole, and fluoroquinolones in 2020. This is making it harder to effectively treat common infections.
17 mar 2021 · Tolerant bacteria disrupt antibiotic efficacy and increase the likelihood that a population gains antibiotic resistance, a growing health concern. We examined how E. coli transcriptional...
25 cze 2024 · Whole-genome sequencing of resistant isolates revealed that ampicillin resistance was acquired via a combination of single-point mutations and amplification of the gene encoding beta-lactamase...
Ampicillin (AMP), a semi-synthetic β-lactam antibiotics, is widely used to treat of human and livestock E. coli infection, but recently its resistance rate has increased. 1–3 AMP works on the active replicating stage of bacteria, inhibiting the synthesis of bacterial cell wall.
Currently, the efficacy of antibiotics is severely affected by the emergence of the antimicrobial resistance phenomenon, leading to increased morbidity and mortality worldwide. Multidrug-resistant pathogens are found not only in hospital settings, ...
Resistance to ampicillin now is common among isolates of H. influenzae, with the incidence in the range of 40% in some communities. 128,129 Ampicillin should never be used alone as empiric therapy of invasive disease.
Salmonella showed widespread resistant to ampicillin which resulted in use of alternative antimicrobials like fluroquinolones and cephalosporins in the treatment of enteric fever in last two decades. Unfortunately there are growing reports of resistance to these antimicrobials.
