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Alpha-blockers promote stone passage in patients receiving shock wave lithotripsy, and may be able to relieve ureteral stent-related symptoms. In the appropriate clinical scenario, the use of α-blockers is recommended in the conservative management of distal ureteral stones. Key words: Alpha-blockers, Ureteral stones, Kidney stones.
- Alpha‐blockers as medical expulsive therapy for ureteral stones
The main findings of this meta‐analysis are that greater...
- Alpha blockers for treatment of ureteric stones: systematic ... - PubMed
There was moderate quality evidence that alpha blockers...
- Alpha‐blockers as medical expulsive therapy for ureteral stones
1 gru 2019 · Evidence-Based Answer. The alpha blocker tamsulosin (Flomax) can be used to improve clearance of stones larger than 5 mm, shorten expulsion times, and reduce hospitalization. (Strength of...
1 gru 2016 · Contemporary practice guidelines from leading professional societies recognize the off-label use of alpha adrenergic antagonists (or alpha blockers) as an initial treatment option for patients with newly diagnosed, uncomplicated ureteric stones <10 mm in size, whose symptoms are controlled.1 2 This endorsement is based on several systematic ...
The main findings of this meta‐analysis are that greater stone clearance can be achieved with medical expulsive therapy with an alpha‐blocker than with standard therapy without an alpha‐blocker (low‐quality evidence).
25 gru 2017 · Data Synthesis: For ureteral stones ≤10 mm treated without lithotripsy, alpha-blockers increased clearance in all meta-analyses and one RCT versus control. For ureteral or renal stones treated with lithotripsy, 4 RCTs and all meta-analyses found benefit with alpha-blockers compared with control.
1 gru 2016 · There was moderate quality evidence that alpha blockers facilitate passage of ureteric stones (risk ratio 1.49, 95% confidence interval 1.39 to 1.61). Based on a priori subgroup analysis, there seemed to be no benefit to treatment with alpha blocker among patients with smaller ureteric stones (1.19, 1.00 to 1.48).
1 lut 2015 · The prevalence of kidney stone disease has increased in recent years and affects 5% to 10% of the population. 1 Alpha blockers relax smooth muscle and decrease intraureteral pressures. The...
