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1. www.frontiersin.org › journals › veterinary-scienceAbnormal Behavior Episodes Associated With Zonisamide in Three...

   www.frontiersin.org › journals › veterinary-science

   • Zapisane w pamięci cache

   28 paź 2021 · MRI study and cerebrospinal fluid analysis in two dogs were unremarkable. The abnormal behavior episodes deteriorated along with gradual dose increment of zonisamide and these episodes almost completely disappeared within 5 days after discontinuation of zonisamide.

2. www.frontiersin.org › journals › veterinary-scienceAbnormalBehaviorEpisodes AssociatedWithZonisamideinThree...

   www.frontiersin.org › journals › veterinary-science

   Although psychiatric adverse effects including aggressive behavior associated with zonisamide are widely recognized in humans, this is the first report in dogs in the clinical setting. Keywords: episodic abnormal behavior, psychiatric adverse effect, anti-seizure drug, zonisamide, dog, epilepsy.

3. puppadogs.com › zonisamide-for-dogs-benefits-dosage-side-effectsZonisamide for Dogs: Benefits, Dosage, Side Effects, and More -...

   puppadogs.com › zonisamide-for-dogs-benefits-dosage-side-effects

   • Zapisane w pamięci cache

   27 sie 2024 · Dogs may become anxious, fearful, or aggressive as a result of frequent seizures. With Zonisamide’s help, these behavioral changes can be mitigated, enabling the dog to maintain a more consistent and pleasant demeanor.

4. onlinelibrary.wiley.com › doi › fullClinical efficacy and tolerability of zonisamide monotherapy in...

   onlinelibrary.wiley.com › doi › full

   23 maj 2024 · Zonisamide (ZNS) is a newer generation antiseizure medication (ASM) used to treat epilepsy in dogs and cats. However, scientific and clinical information, particularly regarding monotherapy, is limited. Objectives. To evaluate the antiseizure efficacy and tolerability of ZNS monotherapy in dogs with newly diagnosed idiopathic epilepsy (IE). Animals

5. bvajournals.onlinelibrary.wiley.com › doi › fullUpdate on seizure and therapeutic drug monitoring in dogs and...

   bvajournals.onlinelibrary.wiley.com › doi › full

   21 sty 2022 · Additional AEDs, such as levetiracetam, zonisamide and gabapentin, may be required for patients with refractory epilepsy (ie, frequent and severe seizures despite appropriate drug therapy).

6. www.ncbi.nlm.nih.gov › pmc › articles2015 ACVIM Small Animal Consensus Statement on Seizure Management...

   www.ncbi.nlm.nih.gov › pmc › articles

   22 lut 2016 · The therapeutic target range for zonisamide of 10–40 μg/mL in people can be used as guidance regarding effective concentrations that can be targeted in dogs. Serum zonisamide concentration should be monitored 1–2 weeks after treatment initiation or dosage adjustment and any time seizure frequency increases.

7. www.ncbi.nlm.nih.gov › pmc › articlesInternational Veterinary Epilepsy Task Force consensus proposal...

   www.ncbi.nlm.nih.gov › pmc › articles

   28 sie 2015 · Since the 1990s, new AEDs with improved tolerability, fewer side effects and reduced drug interaction potential have been approved for the management of epilepsy in humans. Many of these novel drugs appear to be relatively safe in dogs, these include levetiracetam, zonisamide, felbamate, topiramate, gabapentin, and pregabalin.