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Posaconazole (POS) delayed-release tablets (DRT) are favored over the suspension formulation due to once-daily dosing and improved absorption (1 – 4). However, patients with feeding tubes who are unable to swallow whole tablets are occasionally encountered in clinical practice.
3 sty 2024 · Although crushing pills can make taking pills easier, and may even be necessary for some (e.g., those with a feeding tube), it is important to be mindful of which solid oral medications should not be crushed before consumption as it may alter their intended effects due to their specific formulation.
13 kwi 2020 · It’s the dreaded question about crushing that tablet. Of course, the answer’s not in the package insert, so what are YOU supposed to do? Guess what, tl;dr is here with some clues about how to figure out if and when it just might be ok to bend the crushing rules (or not).
25 cze 2021 · Modified-release tablets or capsules (they might have names that include MR, SR, XL or LA) are usually not suitable for crushing or opening. Some (but not all) tablets and capsules that contain modified-release granules can be dispersed or opened.
31 paź 2023 · Some slow-release tablets are scored and can be divided or halved, but not crushed. Examples include Toprol XL (metoprolol succinate) and Sinemet CR (carbidopa and levodopa). Certain long-acting capsules can also be opened and their contents sprinkled without chewing or crushing.
16 sty 2024 · Approximately 11% to 14% of community-dwelling adults ≥65 years old and >30% of residents in skilled nursing or long-term care experience dysphagia. 1-3 Adults with dysphagia or their caregivers may resort to splitting or crushing tablets, often inappropriately, to aid in administration.
1 kwi 2009 · The majority of extended-release products should not be crushed or chewed, although there are some newer slow-release tablet formulations available that are scored and can be divided or halved (e.g., Toprol XL).
