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4 sie 2015 · An irregular Z-line in an esophageal ultrasound indicates an incorrect joining with the gastroesophageal junction at the base of the esophagus. Irregular Z-lines often lead to a diagnosis of Barrett’s esophagus, according to a study published by the National Institutes of Health.
28 lut 2018 · The Z line demarcates the squamocolumnar junction (SCJ), the transition from the squamous esophageal mucosa to the columnar mucosa lining the stomach, or in cases of Barrett’s esophagus, between the squamous and intestinalized columnar epithelium of the metaplastic segment.
15 lis 2021 · The squamocolumnar junction or Z‐line is an endoscopically visible demarcation separating the esophageal squamous epithelium from the red‐colored columnar gastric epithelium. In BE, the salmon‐colored columnar epithelium extends proximally from the EGJ to the esophagus in a continuous manner.
8 lut 2023 · Overview. Barrett's esophagus Enlarge image. Barrett's esophagus is a condition in which the flat pink lining of the swallowing tube that connects the mouth to the stomach (esophagus) becomes damaged by acid reflux, which causes the lining to thicken and become red.
In BE, the squamous epithelium of the distal esophagus is replaced by columnar epithelium, thus displacing the squamocolumnar junction, also called the Z-line, orally, and giving rise to a columnar lined esophagus (CLE). In BE, there is an increased risk of developing esopha-geal adenocarcinoma (EAC) [2].
The histologic hallmark of intestinal metaplasia is required to confirm diagnosis. Biopsy specimens obtained from tissue of presumed Barrett esophagus or an irregular Z line confirm metaplastic glandular mucosa and permit evaluation of dysplastic or neoplastic changes.
1 sie 2024 · An “irregular” z-line refers to an irregular appearing squamocolumnar junction characterized by the presence of columnar mucosa less than 1 cm in length that extends above the gastroesophageal junction.
