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13 sie 2018 · In this work we present a method for imaging whole neurons in the brain, combining synchrotron-based X-ray microtomography with the Golgi-Cox mercury-based impregnation protocol.
25 maj 2022 · X-ray contrast in SXRT can be generated by two mechanisms: absorption and phase shift 79. Staining the protein and lipid distribution in the samples (i.e. their ultrastructure) by passively ...
1 lut 2024 · The X-ray tube contains a filament powered by a step-down transformer to generate heat, creating free electrons near the cathode. A step-up transformer then supplies high voltage to the X-ray tube in two stages, rapidly increasing the potential difference between the cathode and anode.
10 sty 2022 · Here, we built a generalized linear model based on Mie scattering theory that quantitatively links tissue scattering to myelin content and neuron density in the human brain.
Specially, XRM for three-dimensional (3D) imaging of large-scale brain tissue with high resolution and fast imaging speed is highlighted. Additionally, the development of elegant methods for acquisition of brain functions from electrical/chemical signals in the brain is outlined.
22 lut 2018 · To visualize the spatial organization of the ECS in live brain tissue, we developed super-resolution shadow imaging (SUSHI). It is based on 3D-STED microscopy and labeling of the extracellular fluid with a diffusible fluorophore that does not permeate cell membranes.
18 lut 2021 · Ultrastructural observations can provide thorough insights into the cellular and subcellular mechanisms underlying brain function and dysfunction in an unbiased manner, by revealing all cell types and their constituents simultaneously, without the restrictive use of markers that only show the elements of interest.
