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Although disturbances of mood, cognition, sleep, and behavior as well as frank delirium or even psychosis are possible, the most common adverse effects of short-term corticosteroid therapy are euphoria and hypomania. Conversely, long-term therapy tends to induce depressive symptoms.
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26 maj 2020 · Steroid-induced psychosis manifest mild to severe symptoms, ranging from anxiety, insomnia, and irritability to mania, psychosis, delirium, and depression, among others.
The effect of anti-depressive drugs are different, i.e., tricyclic antidepressants could lead to a significant worsening of symptoms, while a selective serotonin reuptake inhibitors, such as fluoxetine, may improve symptoms of depression during corticosteroid therapy as well as phenytoin, lamotrigine, risperidone, quetiapine, and gabapentin.
1 paź 2014 · An illustrative case vignette is presented describing a patient’s experience of cycles of manic-like behavior and depression while on high-dosage prednisone, with long-term cognitive disorganization, vulnerability to stress, and personality changes.
24 sty 1998 · Adrenal steroids are commonly prescribed drugs, the central effects of which are rarely alluded to in routine clinical practice or systematically investigated in medical research. Glucocorticoids are important in the pathogenesis of depression, but this potentially serious psychological side effect is often overlooked in clinical practice.
Mania/hypomania is the most common overall psychiatric symptom; the most common mood manifestations are anxiety and depression.4,5 Other possible ste-roid-induced symptoms include psychosis, dementia, panic disorder, delirium, suicidal thinking and behavior, aggressive behav-ior, insomnia, agitation, depersonalization, and euphoria.5 The most co...
17 paź 2011 · The psychiatric signs, symptoms and syndromes associated with corticosteroid treatment include (DSM-IV substance-induced) mood disorders (hypomania, mania, mixed states, depression), anxiety and panic disorder, 15,16 delirium, suicidal thinking and behavior in the context of affective syndromes or delirium, 12,17–20 aggressive behavior 21 ...
