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17 kwi 2023 · A somatic mutation describes any alteration at the cellular level in somatic tissues occurring after fertilization. These mutations do not involve the germline and consequently do not pass on to offspring.
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A somatic mutation is a change in the DNA sequence of a somatic cell of a multicellular organism with dedicated reproductive cells; that is, any mutation that occurs in a cell other than a gamete, germ cell, or gametocyte.
Study with Quizlet and memorize flashcards containing terms like Which best describes somatic mutations?, A base sequence reads AAGTCG before a mutation. Which could be the base after a frameshift mutation occurs?, The DNA sequence reads ACGTTCATT before a mutation occurs.
Somatic mutation, genetic alteration acquired by a cell that can be passed to the progeny of the mutated cell in the course of cell division. Somatic mutations are frequently caused by environmental factors, such as exposure to ultraviolet radiation or to certain chemicals.
Somatic cells form the tissues of the organism and are not passed on as gametes. Any mutations in somatic cells will only affect the individual in which they occur, not its progeny. If mutations occur in somatic cells, its mutant descendants will exist alongside other non-mutant (wild type) cells.
Somatic mutations include rearrangements and copy number alterations, small insertions and deletions, base substitutions, as well as epigenetic changes. These mutations occur in the genomes of all dividing cells, both normal and neoplastic.
