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Summary: It is well known that chronic alcoholics are at high risk for being deficient in vitamin B1 (thiamine), which is known to put the patient at an increased risk for Wernicke-Korsakoff Syndrome, cerebellar degeneration, and cardiovascular dysfunction.
Oral thiamine is ineffective in thiamine deficiency and should not be used in the initial treatment phase. The preferred route of thiamine ad ministration is intravenous (IV), although intramuscular (IMI) route is acceptable if IV access cannot be obtained or continued.
Alcohol withdrawal. In patients dependent on alcohol, a drop in blood-alcohol concentration may precipitate a withdrawal syndrome. This can occur as early as 6 hours after the last drink. Withdrawal Symptoms: Mild - tremor, agitation, nausea, vomiting, disorientation and anxiety.
6 cze 2024 · Intramuscular and intravenous thiamine can be used to prevent complications of alcohol dependence such as Wernicke’s encephalopathy.
18 lis 2004 · The present letter is intended to provide some element of discussion on thiamine dosage, route of administration and duration of treatment in alcoholics. The daily requirement of thiamine is ∼1.5 mg; on deprivation, TD occurs within 2–3 weeks (Thomson, 2000).
3 lis 2021 · Thiamine deficiency can be treated by stopping alcohol consumption, eating a nutritious diet and by taking vitamin B1 supplements. 1 However, diet and supplements alone are not effective if heavy alcohol use continues because alcohol will block absorption.
12 kwi 2011 · MRI should be used to support the diagnosis of acute WE in patients both with and without alcoholism. Thiamine is indicated for the treatment of suspected or manifest WE, and should be ...
