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WE is a neuropsychiatric complication caused by thiamine (vitamin B1) deficiency, which is characterised by a triad of symptoms: • Confusion • Ataxia (muscle incoordination) • Ophthalmoplegia (paralysis of the ocular muscles) WE often occurs in people with chronic alcohol dependence, with detox being a major risk factor.
26 cze 2023 · Wernicke-Korsakoff syndrome is a common complication of a thiamine deficiency that is primarily seen with alcoholics. This syndrome was classically described as a clinical triad consisting of altered mental status (i.e., confusion or dementia), nystagmus (or ophthalmoplegia), and ataxia.
1 mar 2020 · Given the potential benefit of preventing thiamine deficiency, oral thiamine supplementation is a consideration in the office management of alcohol use disorders and alcohol withdrawal.
12 kwi 2011 · MRI should be used to support the diagnosis of acute WE in patients both with and without alcoholism. Thiamine is indicated for the treatment of suspected or manifest WE, and should be ...
6 cze 2024 · Intramuscular and intravenous thiamine can be used to prevent complications of alcohol dependence such as Wernicke’s encephalopathy.
Oral thiamine is ineffective in thiamine deficiency and should not be used in the initial treatment phase. The preferred route of thiamine administration is intravenous (IV), although intramuscular (IMI) route is acceptable if IV access cannot be obtained or continued.
4 kwi 2022 · Wernicke-Korsakoff syndrome is an unusual type of memory disorder due to a lack of thiamin (vitamin B1) requiring immediate treatment. It most often happens in people with alcohol use disorder and malnutrition.
