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How should alcoholic patients with Wernicke-Korsakoff Syndrome receive thiamine replacement? The current standard of treatment for such patients is to give them thiamine 100 mg intravenously (IV) before administering glucose containing IV fluids and then to continue this dose for several days.
6 cze 2024 · Intramuscular and intravenous thiamine can be used to prevent complications of alcohol dependence such as Wernicke’s encephalopathy.
The standard treatment for alcoholic patients with Wernicke-Korsakoff Syndrome is the administration of 100 mg thiamine IV before glucose-containing IV fluids, followed by several days of thiamine supplementation.
18 lis 2004 · Specifically, the prophylactic treatment for at-risk patients consists of an intramuscular administration of 250 mg thiamine (plus other B vitamins and ascorbic acid), once daily for 3–5 consecutive days.
3 gru 2018 · Thiamine deficiency, in turn, can lead to acute Wernicke encephalopathy, a form of brain damage that causes confusion, vision problems and difficulty moving. The good news is there is a quick, inexpensive treatment for it: intravenous infusion of thiamine as soon as possible after the symptoms appear.
Guideline. Oral thiamine is ineffective in thiamine deficiency and should not be used in the initial treatment phase. The preferred route of thiamine administration is intravenous (IV), although intramuscular (IMI) route is acceptable if IV access cannot be obtained or continued.
5 cze 2021 · A few pilot studies in humans reported beneficial effects of thiamine administration on diabetic nephropathy, but, despite all promising proofs-of-concept, the possible role of thiamine in counteracting development or progression of retinopathy has not been addressed until now.
