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  1. 10 lut 2021 · Our trial showed that among adults with overweight or obesity (without diabetes), once-weekly subcutaneous semaglutide plus lifestyle intervention was associated with substantial, sustained ...

  2. 3 sie 2023 · While the drug—commonly known by brand names such as Ozempic and Wegovy — helps reduce blood glucose to normal levels, it also slows the passage of food through the stomach and reduces appetite,...

  3. 7 sty 2023 · The Semaglutide Treatment Effect in People with Obesity (STEP) Phase 3a clinical development program evaluated the safety and efficacy of the first second-generation medication, namely semaglutide, administered subcutaneously once weekly, for weight management in adults with obesity or overweight with at least one weight-related comorbidity [4 –...

  4. 13 maj 2024 · Metrics. This article has been updated. Abstract. In the SELECT cardiovascular outcomes trial, semaglutide showed a 20% reduction in major adverse cardiovascular events in 17,604 adults with...

  5. Hari notes that his body “felt like a visible sign of failure”. Semaglutide could offer an easier and more reliable way to lose weight and combat the health impacts people with obesity face. Why should this drug, proven to work, not be available to help people change their lives?

  6. 30 paź 2024 · A higher percentage of participants (41.0%) had severe obesity (BMI ≥40) than other weight categories (the BMI was 35 to <40 in 34.4% of the participants, 30 to <35 in 24.3%, and <30 in 0.2% ...

  7. 10 paź 2022 · In summary, in adults with overweight (with at least one weight-related comorbidity) or obesity, semaglutide treatment led to substantial, sustained weight loss over 104 weeks versus placebo.

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