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The chromosome theory of inheritance is based on a few fundamental principles Ð1. Chromosomes contain the genetic material Ð2. Chromosomes are replicated and passed along from parent to offspring Ð3. The nuclei of most eukaryotic cells contain chromosomes that are found in homologous pairs "During meiosis, each homologue segregates into one ...
With each mitotic division, chromosomes replicated, condensed from an amorphous (no constant shape) nuclear mass into distinct X-shaped bodies (pairs of identical sister chromatids), and migrated to separate cellular poles.
independently noted these parallels and began to develop the chromosome theory of inheritance. According to this theory, Mendelian genes have specific loci (positions) along chromosomes, and it is the chromosomes that undergo segregation and independent assortment. As you can see in Figure 15.2, the separation of homo-
1 kwi 2014 · This paper describes this development, beginning with the discovery of DNA as a chemical substance by Friedrich Miescher in 1869, followed by its basic chemical analysis and demonstration of its...
Let’s look at the process and behavior of chromosomes during mitosis and meiosis to see how they qualify for the designation of hereditary material. These are the observations that led to the CTI. II. SOME DEFINITIONS. A. Chromosome sets. Higher organisms contain two similar sets of chromosomes in somatic cells.
The chromosome theory of inheritance Based on the congruence of determinant behavior (Mendel) and chromosome behavior (cytology) The essence of the theory: Proof- Based on tests of predictions: transmission of traits should parallel the segregation of specific chromosomes if chromosome segregation is altered the
Finally, we discuss how eucaryotic cells fold these long DNA molecules into compact chromosomes. This packing has to be done in an orderly fashion so that the chromosomes can be replicated and apportioned correctly between the two daughter cells at each cell division.