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1 cze 2023 · Parkinson-plus syndrome (PPS), also called atypical parkinsonism, refers to a group of neurodegenerative movement disorders that resemble idiopathic Parkinson's disease (PD) with certain distinguishing clinical and pathophysiological features.
• Parkinson-plus syndromes are distinct neurodegenerative diseases that resemble PD but have some additional challenging features and different changes in the brain. • These disorders typically do not respond to levodopa, the mainstay of PD treatment.
DIAGNOSIS OF PARKINSON’S PLUS SYNDROMES: IS THERE A ROLE FOR NEUROPSYCHOLOGY? TROY WEBBER, PH.D. LEARNING OBJECTIVES. List the Parkinson’s disease plus (PD+) syndromes. Recall the onset, course, and core features of the PD+ syndromes. Identify neuropathology and neuroimaging characteristics of the PD+ syndromes.
4 mar 2020 · Parkinson-plus syndromes are clinically and pathologically distinct from PD and combine parkinsonism with prominent additional abnormalities. In this chapter, we discuss the two most common Parkinson-plus disorders: progressive supranuclear palsy (PSP) and multiple system atrophy (MSA).
1 cze 2023 · Parkinson-plus syndrome (PPS), also called atypical parkinsonism, refers to a group of neurodegenerative movement disorders that resemble idiopathic Parkinson's disease (PD) with certain distinguishing clinical and pathophysiological features.
1 lut 2019 · The term atypical parkinsonian disorders (APDs) or Parkinson plus syndromes is used mainly to denote the four major neurodegenerative clinicopathological entities including progressive supranuclear palsy (PSP), corticobasal degeneration (CBD), multiple system atrophy (MSA), and dementia with Lewy bodies (DLB).
Overview. Aetiology and pathogenesis of Parkinson’s disease. Differential diagnosis of Parkinsonism. Video examples of Parkinson’s disease mimics and rare causes. Pathology. Neuronal loss in substantia nigra and widespread α-synuclein deposition. Results in striatal dopamine deficiency. Dopamine plays an important role in the brain.
