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6 sty 2024 · In medical terms, "nadir" could mean the lowest concentration of a drug in the body. Regarding chemotherapy, it typically describes the point at which blood cell counts are at their lowest after a chemotherapy treatment.
What Is Nadir? When discussing chemotherapy side effects you may hear the term nadir used, usually in reference to the blood counts, particularly white blood cell count and platelet count. Nadir basically means low point, however further explanation may clarify this term in connection with chemotherapy treatment.
WHAT IS NADIR? Nadir is a term that basically means low point. When a person with cancer reaches their “nadir” following each chemotherapy cycle, it means that the person’s blood cell counts are the lowest they will be during that treatment cycle. Each chemotherapy treatment comes with a nadir period.
Introduction: We analyzed time to CA19-9 nadir during first-line chemotherapy in patients with metastatic, unresectable, and borderline resectable pancreatic ductal adenocarcinoma (PDAC) to investigate the relationship between biomarker response and duration of chemotherapy.
14 paź 2021 · Slow tumor growth rates after nadir are associated with longer overall survival in patients with EGFR-mutant advanced NSCLC treated with erlotinib, which remained significant after adjusting for time to nadir and other clinical variables.
7 wrz 2017 · Nadir PSA at 0.06 is a strong independent predictor of BFS in patients with intermediate or high risk prostate cancer treated by definitive EBRT and ADT. Intermediate and high risk localized prostate cancers (PrCa) are effectively treated by definitive external beam radiation therapy (EBRT) in combination with androgen deprivation therapy (ADT).
1 lip 2018 · Nadir hemoglobin levels during chemoradiotherapy may stratify lung cancer patients. We investigated the influence of change in hemoglobin (Hgb) levels during concurrent chemoradiotherapy (C-CRT) on outcomes of non-anemic patients with stage IIIA/B non-small cell lung cancer (NSCLC).
