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23 sie 2017 · Microtubule nucleation is stimulated and can be controlled by the following two principal activities: by providing a stable template (such as the γ-tubulin ring complex (γTuRC) or a severed...
1 paź 2012 · Microtubules are hollow cylindrical polymers that are assembled from heterodimers composed of α- and β-tubulin. The longitudinal orientation of the tubulin dimers provides microtubules with an intrinsic polarity, with α-tubulin facing the so-called minus end and β-tubulin the so-called plus end.
In cell biology, microtubule nucleation is the event that initiates de novo formation of microtubules (MTs). These filaments of the cytoskeleton typically form through polymerization of α- and β-tubulin dimers, the basic building blocks of the microtubule, which initially interact to nucleate a seed from which the filament elongates. [1]
Microtubules are the structural center of neurons, stretching in overlapping arrays from the cell body to the far reaches of axons and dendrites. They also act as the tracks for long-range transport mediated by dynein and kinesin motors.
10 paź 2011 · Microtubule nucleation is controlled by the γ-tubulin ring complex (γTuRC) and related γ-tubulin complexes, providing spatial and temporal control over the initiation of microtubule growth.
24 maj 2021 · Interphase plant cells require microtubule-dependent microtubule nucleation to generate cortical microtubule networks at mixed angles, an arrangement that supports cell and leaf morphology, and to reorient their microtubule networks to alter the direction of plant growth in response to light.
22 cze 2015 · Our results explain how MAPs establish the spatial and temporal profile of microtubule nucleation. Microtubule nucleation is the process by which soluble αβ-tubulin subunits are first converted...
