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5 lip 2024 · Memantine (brand name Namenda) is an oral NMDA blocker that may be used to treat moderate to severe dementia in people with Alzheimer’s disease. Memantine is an NMDA (N-methyl-D-aspartate) blocker that works by binding to NMDA-receptor-operated cation channels and blocking their effect.
6 cze 2023 · Memantine is a noncompetitive moderate‐affinity strong voltage‐dependent N‐methyl‐D‐aspartate receptor antagonist. It has been used to treat Alzheimer's disease (AD) since 1989. In 2018, it became the second most commonly used drug for the treatment of dementia in the world.
2 mar 2007 · Memantine, an NMDA receptor antagonist has been found to be effective, both as monotherapy and in combination with donepezil, in the treatment of patients with moderate to severe stage AD.
13 mar 2018 · Memantine (MEM), an antagonist of extrasynaptic NMDAR, is currently used for the treatment of AD jointly with acetylcholinesterase inhibitors.
Memantine is in a class of medications called NMDA receptor antagonists. It works by decreasing abnormal activity in the brain. Memantine may improve the ability to think and remember or may slow the loss of these abilities in people who have AD.
Memantine works by blocking the effects of a chemical called glutamate. Glutamate sends messages between nerve cells in the brain. Nerve cells damaged by Alzheimer's disease make too much glutamate which can cause more damage.
Memantine is a medication that comes in a tablet form. It treats dementia caused by Alzheimer’s disease. Dementia affects your thinking, memory, reasoning, personality, mood and behavior.
