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30 lis 2019 · Gout is characterized biochemically by extracellular fluid urate saturation, which is reflected by hyperuricemia in the blood, with plasma or serum urate concentrations exceeding 6.8 mg/dL (approximately 400 µmol/L); this level is the approximate limit of urate solubility. [5]
Gout (/ ɡaʊt / GOWT[ 9 ]) is a form of inflammatory arthritis characterized by recurrent attacks of pain in a red, tender, hot, and swollen joint, [ 4 ][ 10 ] caused by the deposition of needle-like crystals of uric acid known as monosodium urate crystals. [ 11 ]
28 mar 2022 · Gout is a metabolic disorder which causes inflammation of the joints. During acute episodes, certain joints swell up within just a few hours and become very sensitive to pain. The inflammation is triggered by tiny needle-shaped crystals of uric acid that mainly build up in the joints.
29 lis 2022 · Gout is a form of inflammatory arthritis that results from an excess of uric acid in the blood. Among people with gout, 90% have kidneys that don’t adequately remove uric acid from their urine, while 10% have high uric acid levels because they produce too much uric acid.
17 lis 2022 · Gout is a syndrome characterised by: hyperuricaemia and deposition of urate crystals causing attacks of acute inflammatory arthritis; tophi around the joints and possible joint destruction; renal glomerular, tubular, and interstitial disease; and uric acid urolithiasis.
Gout is a disorder in which deposits of uric acid crystals accumulate in the joints because of high blood levels of uric acid (hyperuricemia). The accumulations of crystals cause flares (attacks) of painful inflammation in and around joints. Accumulations of uric acid crystals can intermittently cause severe joint or tissue pain and inflammation.
18 sie 2023 · Gout is a form of arthritis caused by high uric acid levels in the blood. The acid can form crystals in the joints with sharp edges that inflame the joint, causing severe pain and swelling. People can develop high uric acid levels due to genetic predisposition and eating foods high in purines.
