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Drugs—natural and synthetic alike—are chemicals used for medicinal purposes. They interact with complex chemical systems of humans or animals. Medicinal chemistry is concerned with this interaction, focusing on the organic and biochemical reactions of drug substances with their targets. This is one aspect of drug chemistry.
INTRODUCTION. Xenobiotic metabolism, which includes drug metabolism, has become a major pharmacolo-gical science with particular relevance to biol-ogy, therapeutics and toxicology.
This chapter introduces biochemical pharmacology and highlights drug absorption and drug transformation reactions and a general introduction to pharmacology, drug discovery and clinical trials for new drug candidates. It also introduces the concept of individualization of drug therapies.
INTRODUCTION TO MEDICINAL CHEMISTRY The subject of medicinal chemistry explains the design and production of compounds that can be used for the prevention, treatment or cure of human and animal diseases. Medicinal chemistry includes the study of already existing drugs, of their biological properties and their structure activity relationships.
1 sty 2015 · A common narrower definition of pharmacology concentrates on the fate and effects of a drug in the body. Clinical chemistry, a different subject, is concerned with the determination of physiological and pathophysiological parameters in body fluids, such as enzyme activities and metabolites in blood and urine.
11 sie 2005 · Starting with an overview of basic principles, Medicinal Chemistry examines the properties of drug molecules, the characteristics of drug receptors, and the nature of drug-receptor interactions. Then it systematically examines the various families of receptors involved in human disease and drug design.
An introduction to drugs, their action and discovery 1.1 Introduction The primary objective of medicinal chemistry is the design and discovery of new compounds that are suitable for use as drugs. This process involves a team of workers from a wide range of disciplines such as chemistry, biology, biochemistry, pharmacology,
