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24 paź 2024 · DNA ligase is an essential enzyme that plays a critical role in the integrity and maintenance of DNA within living organisms. Its primary function is to facilitate the joining of DNA strands by catalyzing the formation of phosphodiester bonds, a crucial process in DNA repair, replication, and recombination.
3 sie 2023 · DNA ligase is an enzyme that catalyzes the ligation reaction, ligation is the process of joining various types of DNA fragments. DNA ligase joins the DNA molecule covalently by catalyzing the formation of phosphodiester bonds between adjacent nucleotides.
DNA ligase is a type of enzyme that facilitates the joining of DNA strands together by catalyzing the formation of a phosphodiester bond. It plays a role in repairing single-strand breaks in duplex DNA in living organisms, but some forms (such as DNA ligase IV) may specifically repair double-strand breaks (i.e. a break in both complementary ...
5 paź 2023 · DNA ligase is an enzyme that joins DNA strands through the formation of phosphodiester bonds in a process called DNA ligation. The bond in double-stranded DNA is formed by joining the 5′ phosphate and 3′ hydroxyl termini of DNA strands, using ATP as a coenzyme.
DNA ligase catalyzes a strand-joining reaction at a nick junction formed by the annealing of two DNA strands on a DNA template. The requirement of base-pair complementarity at the nick junction has been explored to develop ligase-based technologies for the detection of sequence variance.
6 wrz 2023 · DNA ligase is an enzyme that catalyzes the formation of a covalent bond between a 5’ phosphate and a 3’ hydroxyl group at the termini of DNA fragments; this bond ligates the two DNA fragments together.
DNA ligase is an enzyme that repairs DNA breaks by joining the 5´-phosphorylated ends of broken DNA to the 3´-OH ends, repairing breaks in the phosphate backbone of DNA.
