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The differential diagnosis of true muscle weakness is extensive, including neurologic, rheumatologic, endocrine, genetic, medication- or toxin-related, and infectious etiologies. A stepwise...
Clinical clues, including preserved foot muscle bulk in the setting of bilateral foot drop, preservation of intrinsic hand muscle function in the setting of prominent finger extensor weakness, and concurrent neck or proximal limb muscle weakness, suggest primary muscle disease rather than neuropathy. Figure 1.
The differential diagnosis of inflammatory myopathy is broad and includes conditions that present with myalgia, weakness, or serum creatine kinase elevation or any combination of these features, and may or may not be asso-ciated with an infiltrate of inflammatory cells on muscle biopsy.
15 sty 2020 · The differential diagnosis of true muscle weakness is extensive, including neurologic, rheumatologic, endocrine, genetic, medication- or toxin-related, and infectious etiologies. A stepwise approach to narrowing this differential diagnosis relies on the history and physical examination combined with knowledge of the potential etiologies.
The distal myopathies are a rare and heterogeneous group of disorders causing myopathic weakness at onset of the hands, feet, or both.1 The term distal myopathy is usually reserved for genetic disorders; however, weakness of the distal muscles is sometimes present in the acquired muscle diseases.2 In addition, prominent distal muscle weakness is...
Differential Diagnosis of Distal Myopathies. The era of clinical molecular genetics has refined diagnosis and will hopefully lead to disease-modifying treatments. Kevin J. Felice, DO.
When a patient presents with symptoms of distal numbness, tingling and pain, or weak-ness, the first step is to determine whether the symptoms are the result of periph-eral neuropathy or of a...
