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6 lip 2023 · ADAR regulates the tumor immune microenvironment and can be used as a biomarker of the tumor immunotherapy response, providing a novel strategy for the treatment of tumors, especially bladder cancer.
25 maj 2022 · Therapeutic activation of ZBP1-induced necroptosis provides a readily translatable avenue for rekindling the immune responsiveness of ICB-resistant human cancers.
Around 60% of people living with cancer are aged 65 years or older. Older cancer patients face a unique set of age-associated changes, comorbidities and circumstances that impact on their quality of life (QoL) in ways that are different from those affecting younger patients.
6 lip 2019 · We explore the use of RPs to gain insight in the experiences of patients with advanced cancer. Eighteen patients with advanced cancer were asked to draw a RP expressing how they experienced living with cancer, followed by a semi‐structured interview.
4 mar 2022 · pro-oncogenic role in a growing list of cancer types, and its function in cancer has been attributed to diverse mechanisms. Here, we review existing literature on ADAR1 biology and function, its roles in human disease including cancer, and summarize known cancer-associated phenotypes and mechanisms. Lastly,
Older people with cancer remain under-represented in primary research, especially in randomised controlled trials. Although this has been flagged as a research concern for decades, a worrying analysis shows that inclusion of older patients with cancer in primary research is in fact decreasing.
This guide supports healthcare professionals to provide holistic needs assessments, care and support planning for people living with cancer.
