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Vulval (or vulvar) intraepithelial neoplasia is a pre-cancerous skin lesion (a type of squamous cell carcinoma in situ) that can affect any part of the vulva. The term vulval intraepithelial neoplasia describes two conditions with different biological behaviour: usual type and differentiated type.
29 mar 2023 · Vulval intraepithelial neoplasia or VIN is when abnormal cells develop in the top layer of skin covering the vulva. It is not vulval cancer but could turn into cancer. This may take many years.
Precancer vulvar dysplasia similarly to precancer cervical dysplasia was classified as VIN 1, VIN 2 and VIN 3. Nowadays, according to pathological changes it has been divided into uVIN and dVIN.
24 lip 2023 · VIN 2 means that the growth has a depth of less than two-thirds of the depth of the top vulvar skin layer. VIN 2 has a higher risk of progressing to cancer...
18 paź 2023 · Vulvar intraepithelial neoplasia (VIN) is a noninvasive squamous lesion and precursor of squamous cell carcinoma of the vulva. This activity reviews the evidence-based approaches to diagnosing and managing VIN and focuses on current advancements in histopathological classification and risk stratification of VIN lesions.
Gross findings. Low-grade uVIN presents usually as single or multiple pale-whitish areas, whereas high-grade uVIN presents as multifocal raised plaques or papules that tend to coalesce. A small percentage of the lesions (10%) may be hyperpigmented.
Vulvar intraepithelial neoplasia (VIN) is an increasingly common problem, particularly among women in their 40s. Data from the U.S. Surveillance, Epidemiology, and End Results program demonstrate that VIN incidence increased more than fourfold between 1973 and 2000 1.
