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  1. Precancer vulvar dysplasia similarly to precancer cervical dysplasia was classified as VIN 1, VIN 2 and VIN 3. Nowadays, according to pathological changes it has been divided into uVIN and dVIN.

    • VIN

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  2. Vulval (or vulvar) intraepithelial neoplasia is a pre-cancerous skin lesion (a type of squamous cell carcinoma in situ) that can affect any part of the vulva. The term vulval intraepithelial neoplasia describes two conditions with different biological behaviour: usual type and differentiated type.

  3. Gross findings. Low-grade uVIN presents usually as single or multiple pale-whitish areas, whereas high-grade uVIN presents as multifocal raised plaques or papules that tend to coalesce. A small percentage of the lesions (10%) may be hyperpigmented.

  4. 24 lip 2023 · VIN 2 means that the abnormal growth has a depth of less than two-thirds of the top layer of vulvar skin. Not everyone has symptoms of VIN 2. It’s sometimes diagnosed because...

  5. 29 mar 2023 · Vulval intraepithelial neoplasia or VIN is when abnormal cells develop in the top layer of skin covering the vulva. It is not vulval cancer but could turn into cancer. This may take many years.

  6. Vulvar intraepithelial neoplasia (VIN) is an increasingly common problem, particularly among women in their 40s. Data from the U.S. Surveillance, Epidemiology, and End Results program demonstrate that VIN incidence increased more than fourfold between 1973 and 2000 1.

  7. Summary. Growing evidence has established two major types of vulvar intraepithelial neoplasia (VIN), which correspond to two distinct oncogenic pathways to vulvar squamous cell carcinoma (VSCC). While the incidence of VSCC has remained relatively stable over the last three decades, the incidence of VIN has increased.

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